kobe2602 is a novel and effective small-molecule compound inhibiting Ras¨CRaf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-Ras¡¤GTP to c-Raf-1 RBD with a Ki value of 149 ¡À 55 ¦ÌM.

June 21, 2017

prudect name : kobe2602 is a novel and effective small-molecule compound inhibiting Ras¨CRaf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-Ras¡¤GTP to c-Raf-1 RBD with a Ki value of 149 ¡À 55 ¦ÌM.
Kobe 2602

Synonyms: CAS NO: 454453-49-7Molecular Formula: C₁₄H₉F₄N₅O₄SMolecular Weight: 419.31Purity: 98% minSolubility: in DMSOStorage: -20oC

LEE-011 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1852137