Irinotecan is main use is in colon cancer, particularly in combination with other chemotherapy agents. The cytotoxicity of irinotecan and SN-38 in the two cell lines was as followed: irinotecan IC(50) values were 15.8 ¦ÌM for LoVo cells and 5.17 ¦ÌM for HT-29 cells; SN-38 IC(50) values were 8.25 nM for LoVo cells and 4.50 nM for HT-29 cells.

June 21, 2017

prudect name : Irinotecan is main use is in colon cancer, particularly in combination with other chemotherapy agents. The cytotoxicity of irinotecan and SN-38 in the two cell lines was as followed: irinotecan IC(50) values were 15.8 ¦ÌM for LoVo cells and 5.17 ¦ÌM for HT-29 cells; SN-38 IC(50) values were 8.25 nM for LoVo cells and 4.50 nM for HT-29 cells.
Irinotecan

Synonyms: CAS NO: 97682-44-5Molecular Formula: C₃₃H₃₈N₄O₆Molecular Weight: 586.69Purity: 99%Solubility: Storage: −20°C 2 years

R7204 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519566