GSK690693 is an aminofurazan-derived£¬novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor. It is selective for the Akt isoforms(inhibits Akt kinases 1, 2, and 3 with IC50 values of 2, 13, and 9 nM respectively)versus the majority of kinases in other families; however, it does inhibit additional members of the AGC kinase family.

June 21, 2017

prudect name : GSK690693 is an aminofurazan-derived£¬novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor. It is selective for the Akt isoforms(inhibits Akt kinases 1, 2, and 3 with IC50 values of 2, 13, and 9 nM respectively)versus the majority of kinases in other families; however, it does inhibit additional members of the AGC kinase family.
GSK 690693

Synonyms: CAS NO: 937174-76-0Molecular Formula: C₂₁H₂₇N₇O₃Molecular Weight: 425.48Purity: 98% minSolubility: In DMSOStorage: −20°C

GS4997 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18515537