G-4592 is an oral inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase in clinical development for the treatment of anemia. FG-4592 stabilizes the activitiues of HIF, a cytosolic transcription factor, leading to activation of the genes associated with erythropoiesis, including EPO and enzymes involved in iron metabolism.

June 21, 2017

prudect name : G-4592 is an oral inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase in clinical development for the treatment of anemia. FG-4592 stabilizes the activitiues of HIF, a cytosolic transcription factor, leading to activation of the genes associated with erythropoiesis, including EPO and enzymes involved in iron metabolism.
FG-4592

Synonyms: CAS NO: 808118-40-3Molecular Formula: C₁₉H₁₆N₂O₅Molecular Weight: 352.11Purity: 98% minSolubility: In DMSOStorage: −20°C

BAY73-4506 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18515319