Epirubicin hydrochloride is the hydrochloride salt of the 4¡¯-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation.

June 21, 2017

prudect name : Epirubicin hydrochloride is the hydrochloride salt of the 4¡¯-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation.
Epirubicin hydrochloride

Synonyms: CAS NO: 56390-09-1Molecular Formula: C₂₇H₂₉NO₁₁.HClMolecular Weight: 579.99Purity: 98%Solubility: In DMSOStorage: −20°C 2 years

AZD-2014 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18514375