EPZ-005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.

June 21, 2017

prudect name : EPZ-005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.
EPZ005687

Synonyms: CAS NO: 1396772-26-1Molecular Formula: C₃₂H₃₇N₅O₃Molecular Weight: 539.67Purity: 98% minSolubility: Storage: -20¡æ

BI-6727 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18512269