Decitabine is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines.Decitabine was demonstrated to have a wide range of anti-metabolic activities when tested against cultured cancer cells and to be an effective chemotherapeutic agent for acute myelogenous leukemia. However, because of 5-azacytidine

June 21, 2017

prudect name : Decitabine is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines.Decitabine was demonstrated to have a wide range of anti-metabolic activities when tested against cultured cancer cells and to be an effective chemotherapeutic agent for acute myelogenous leukemia. However, because of 5-azacytidine
Decitabine

Synonyms: CAS NO: 2353-33-5Molecular Formula: C₈H₁₂N₄O₄Molecular Weight: 228.20Purity: 99%Solubility: In DMSOStorage: −20°C 2 years

TAK242 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511281