D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to ¦Á¦Â-Tubulin. D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). D-64131 prevents growth of tumor models in mice following oral administration in vivo. D-64131 has significant potential in cancer treatment.

June 21, 2017

prudect name : D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to ¦Á¦Â-Tubulin. D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). D-64131 prevents growth of tumor models in mice following oral administration in vivo. D-64131 has significant potential in cancer treatment.
D-64131

Synonyms: CAS NO: 74588-78-6Molecular Formula: C₁₆H₁₃NO₂Molecular Weight: 251.28Purity: 98% minSolubility: In DMSOStorage: -20°C

CUDC101 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18510961