Cidofovir(Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis. (IC50= 0.94 ¦ÌM) A wild type HCMV laboratory strain (AD 169) and 3 ganciclovir-resistant clinical isolates(generated as a result of Ganciclovir therapy) that are cross-resistant to cidofovir were also included in the cidofovir susceptibility assays. AD 169 showed a cidofovir IC50 value of 0.6 pM, and the ganciclovir- resistant isolates showed cidofovir IC50 values ranging from 2.3 to 16 pM

June 21, 2017

prudect name : Cidofovir(Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis. (IC50= 0.94 ¦ÌM) A wild type HCMV laboratory strain (AD 169) and 3 ganciclovir-resistant clinical isolates(generated as a result of Ganciclovir therapy) that are cross-resistant to cidofovir were also included in the cidofovir susceptibility assays. AD 169 showed a cidofovir IC50 value of 0.6 pM, and the ganciclovir- resistant isolates showed cidofovir IC50 values ranging from 2.3 to 16 pM
Cidofovir

Synonyms: CAS NO: 113852-37-2Molecular Formula: C8H14N3O6PMolecular Weight: 279.19Purity: 98% minSolubility: In DMSOStorage: −20°C


BBI503 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508807,16680138