CX-6258 is a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. CX-6258 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models. Inhibition of Pim kinases is expected to have a beneficial effect as cancer therapy.

June 21, 2017

prudect name : CX-6258 is a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. CX-6258 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models. Inhibition of Pim kinases is expected to have a beneficial effect as cancer therapy.
CX-6258

Synonyms: CAS NO: 1202916-90-2Molecular Formula: C₂₆H₂₄ClN₃O₃Molecular Weight: 461.94Purity: 98% minSolubility: In DMSOStorage: -20°C

ASP2215 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508720