CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFR¦Â and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2

June 21, 2017

prudect name : CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFR¦Â and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2
CEP 32496

Synonyms: CEP-32496CAS NO: 1188910-76-0Molecular Formula: C₂₄H₂₂F₃N₅O₅Molecular Weight: 517.46Purity: 98% minSolubility: DMSOStorage: -20¡æ

SOM 230 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18507030