Bafetinib (INNO-406) is an orally available, dual Abl/Lyn kinase inhibitor that is up to 55-times more potent than imatinib in Bcr-Abl cell lines. Numerous Bcr-Abl mutant proteins (not T315I) are sensitive to INNO-406 in vitro. INNO-406 demonstrates specific Src kinase activity against Lyn kinase.

June 21, 2017

prudect name : Bafetinib (INNO-406) is an orally available, dual Abl/Lyn kinase inhibitor that is up to 55-times more potent than imatinib in Bcr-Abl cell lines. Numerous Bcr-Abl mutant proteins (not T315I) are sensitive to INNO-406 in vitro. INNO-406 demonstrates specific Src kinase activity against Lyn kinase.
Bafetinib(INNO-406)

Synonyms: Bafetinib (INNO-406)CAS NO: 887650-05-7Molecular Formula: C₃₀H₃₁F₃N₈OMolecular Weight: 576.62Purity: 98% minSolubility: In DMSOStorage: -20°C

1092351-67-1 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18503590