BMS-345541 is a cell-permeable quinoxaline compound that shows anti-inflammatory properties. BMS-345541 is a potent, selective, and allosteric site-binding inhibitor of IKK ¦Â (IKK-2). Displays ~10-fold greater selectivity over IKK ¦Á (IKK-1) and no activity towards IKK¦Å and a panel of more than 15 unrelated protein kinases even at concentrations as high as 100 ¦ÌM. Inhibits cellular I¦ÊB¦Á phosphorylation.

June 21, 2017

prudect name : BMS-345541 is a cell-permeable quinoxaline compound that shows anti-inflammatory properties. BMS-345541 is a potent, selective, and allosteric site-binding inhibitor of IKK ¦Â (IKK-2). Displays ~10-fold greater selectivity over IKK ¦Á (IKK-1) and no activity towards IKK¦Å and a panel of more than 15 unrelated protein kinases even at concentrations as high as 100 ¦ÌM. Inhibits cellular I¦ÊB¦Á phosphorylation.
BMS-345541

Synonyms: IKK Inhibitor IIICAS NO: 445430-58-0;547757-23-3(HCL)Molecular Formula: C₁₄H₁₇N₅Molecular Weight: 255.32Purity: 98% minSolubility: In DMSOStorage: -20° C

AMG232 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18504134