ATP citrate lyase (ACL) inhibitor (IC50 = 0.13 ¦ÌM for human recombinant ACL); blocks lipid synthesis (IC50 = 8 ¦ÌM in HepG2 cells). Displays no cytotoxicity up to a concentration of 50 ¦ÌM. Lowers plasma glucose and triglycerides in a mouse model of hyperlipidemia. Orally bioavailable.

June 21, 2017

prudect name : ATP citrate lyase (ACL) inhibitor (IC50 = 0.13 ¦ÌM for human recombinant ACL); blocks lipid synthesis (IC50 = 8 ¦ÌM in HepG2 cells). Displays no cytotoxicity up to a concentration of 50 ¦ÌM. Lowers plasma glucose and triglycerides in a mouse model of hyperlipidemia. Orally bioavailable.
BMS 303141

Synonyms: CAS NO: 943962-47-8Molecular Formula: C₁₉H₁₅Cl₂NO₄SMolecular Weight: 424.3Purity: 98% minSolubility: In DMSOStorage: -20°C

160098-96-4 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18503031