BML-190 has 50-fold selectivity for CB2 receptors over CB1 receptors. In HEK-293 cells stably expressing the human CB2 receptor, BML-190 potentiates the forskolin-stimulated accumulation of cAMP. BML-190 reduces the basal levels of inositol phosphate production in cells expressing the CB2 BML-190 is an aminoalkylindole. BML-190 is found to yield at least 15 metabolic products.BML-190 diminishes LPS-induced NO and IL-6 production in a concentration-dependent manner. BML-190 also inhibits LPS-induced PGE2 production and COX-2 induction.

June 21, 2017

prudect name : BML-190 has 50-fold selectivity for CB2 receptors over CB1 receptors. In HEK-293 cells stably expressing the human CB2 receptor, BML-190 potentiates the forskolin-stimulated accumulation of cAMP. BML-190 reduces the basal levels of inositol phosphate production in cells expressing the CB2 BML-190 is an aminoalkylindole. BML-190 is found to yield at least 15 metabolic products.BML-190 diminishes LPS-induced NO and IL-6 production in a concentration-dependent manner. BML-190 also inhibits LPS-induced PGE2 production and COX-2 induction.
BML 190

Synonyms: CAS NO: 2854-32-2Molecular Formula: C₂₃H₂₃ClN₂O₄Molecular Weight: 426.89Purity: 98% minSolubility: In DMSOStorage: −20°C

58880-19-6 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18502941