BI 2536 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1, derived from human, mouse and rat) (with IC50of 0.83 nM), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations.

June 21, 2017

prudect name : BI 2536 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1, derived from human, mouse and rat) (with IC50of 0.83 nM), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations.
BI 2536

Synonyms: CAS NO: 755038-02-9Molecular Formula: C₂₈H₃₉N₇O₃Molecular Weight: 521.66Purity: 98% minSolubility: In DMSOStorage: −20°C

154447-36-6 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1850326