AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ER¦Á degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer.

June 21, 2017

prudect name : AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ER¦Á degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer.
AZD9496

Synonyms: CAS NO: 1639042-08-2Molecular Formula: C₂₅H₂₅F₃N₂O₂Molecular Weight: 442.47Purity: 98% minSolubility: DMSOStorage: -20¡æ

936091-26-8 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18500437