AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.

June 21, 2017

prudect name : AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.
AVL-292

Synonyms: CAS NO: 1202757-89-8Molecular Formula: C₂₂H₂₂FN₅O₃Molecular Weight: 423.44Purity: 98% minSolubility: in DMSOStorage: -20oC

25316-40-9 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18498250