AP23848 is a potent Bcr-Abl inhibitor. In a murine model, AP23848 inhibited activation-loop mutant Kit phosphorylation and tumor growth.

June 21, 2017

prudect name : AP23848 is a potent Bcr-Abl inhibitor. In a murine model, AP23848 inhibited activation-loop mutant Kit phosphorylation and tumor growth.
AP23848 PF-562771

Synonyms: CAS NO: 834894-21-2Molecular Formula: C₃₀H₃₈N₅O₂PMolecular Weight: 531.63Purity: 98% minSolubility: In DMSOStorage: -20°C

944396-07-0 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18496816