AMG 925 is a potent and selective dual inhibtor of CDK4/FLT3 with IC50s of 1.5 nM and 2.4 nM for CDK4 and FLT3, respectively; with IC50 of 19 nM in MOLM-13 cell. IC50 value: 1.5/2.4 nM (CDK4/FLT3)

June 21, 2017

prudect name : AMG 925 is a potent and selective dual inhibtor of CDK4/FLT3 with IC50s of 1.5 nM and 2.4 nM for CDK4 and FLT3, respectively; with IC50 of 19 nM in MOLM-13 cell.
IC50 value: 1.5/2.4 nM (CDK4/FLT3)

AMG 925

Synonyms: CAS NO: 1401033-86-0Molecular Formula: C26H29N7O2Molecular Weight: 471.55Purity: 98% minSolubility: In DMSOStorage: -20 oC


675576-98-4 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18500914